Ïã¸ÛÁùºÏ²Ê½ÁÖéÖ±²¥

Skip to main content

Research degrees

Research students are welcomed to Ïã¸ÛÁùºÏ²Ê½ÁÖéÖ±²¥ as valued members of our thriving, research-intensive community. Find out more about in Ïã¸ÛÁùºÏ²Ê½ÁÖéÖ±²¥. A research degree provides the opportunity to investigate a topic in depth, and contribute new knowledge to your discipline.

Proposed PhD Projects

Description
Supervisor
Funding
Hypoxia-driven macrophage modulation in cancer and its impact on T cell immunotherapy
Hypoxia is a common feature of solid tumours. It presents a significant challenge to effective cancer treatment using immunotherapy. Macrophages are known to be recruited to hypoxic regions of the tum...
Self Funded
Development of a novel PCR-based assay to evaluate CAR-T safety using a human-based genotoxicity model
The project on offer is to develop a model for the evaluation of safety when using immunotherapy. CAR-T therapy is currently a novel approach to treat cancer using T cells infected by lentivirus vecto...
Self Funded
3D printing of scaffolds for tissue engineering and regenerative medicine
This project aims to develop multifunctional novel bioactive tissue scaffolds using 3D printing, biomaterials science and controlled drug delivery systems to enhance tissue regeneration. Tissue scaffo...
Self Funded
The role of PE/PPE proteins in tuberculosis
Tuberculosis remains one of the world’s biggest killers due to an infectious disease. There remains an urgent need for the development of effective vaccines and novel drug targets against the disease....
Self Funded
Investigating molecular disease mechanisms and therapy of Friedreich ataxia
Friedreich ataxia (FRDA) is a lethal inherited disease caused by GAA trinucleotide repeat expansion mutation within the FXN gene, leading to epigenetic modification of the FXN gene, decreased levels o...
Self Funded
Repo-Man function in embryogenesis and differentiation
Repo-Man (CDCA2) is a Protein Phosphatase 1 (PP1) targeting subunit that has been shown to be an important regulator of cell division. Recent studied from our laboratory have also shown that that Repo...
Self Funded
Inhibiting cell metabolism to enhance tumour cell death
As you read this, millions of your cells from your body are dying. Do not panic – this is not bad news. Most of them are either superfluous or potentially harmful, so you are better off without them. ...
Self Funded
Study of the exosomes: RNA composition of exosomes as potential biomarkers for cancer; Exosomes as a delivery vehicle for therapeutic shRNAs
Exosomes are membrane microvesicles that are secreted by many cell types and the tumour cells are thought to generate a larger number of such vesicles. Exosomes contain a large set of the specific RNA...
Self Funded
The effect on genome behaviour of growing cells in 3D matricies
There has been a small amount of evidence in the literature that growing cells in 3D scaffolds instead of 2D monolayers alters genome behaviour and organisation such that nuclear structure is altered ...
Self Funded
Telomere length elongation following treatment with chemotherapeutic drugs.
Aim:  To investigate the mechanisms which leads to telomere length elongation after treatment with tricostatin A and azacytidine. Telomeres are specialised structures, which are present at the ends of...
Self Funded

 

Funding for doctoral studies

A number of studentships and other research funding opportunities are available at Ïã¸ÛÁùºÏ²Ê½ÁÖéÖ±²¥. Please see full list here: . 

Choosing your supervisor

Our researchers create knowledge and advance understanding, and equip versatile graduates with the confidence to apply what they have learnt for the benefit of society. Browse the list of the members of our Theme to select your potential supervisor here. You are welcome to approach your potential supervisor directly to discuss your research interests.

All research degrees are administered by the Postgraduate Programmes Office in Colleges. Once you have identified your area of research and a potential supervisor, please use the contact details provided for enquiries.